St. Louis Children’s Hospital and WashU Medicine will open a 133,000 SF outpatient pediatric specialty care center in Wentzville in late 2027. The three story facility topped out July 7 and will house more than 20 specialties, urgent care, a four bed sleep lab and outpatient surgery.
A three story pediatric outpatient facility is taking shape in Wentzville, Missouri, where St. Louis Children’s Hospital and WashU Medicine plan to open a 133,000 SF specialty care center in late 2027. Leaders from both organizations gathered July 7 for a topping-out ceremony marking completion of the building’s structural frame.
This will be the third specialty care center the two institutions have developed in the St. Louis region. Their first opened in 2015 in west St. Louis County near the Highway 40/64 and Mason Road interchange, and a second followed in 2021 in South County near I-55 and Butler Hill Road. Wentzville extends the network into western St. Charles County, one of the fastest growing areas in the state.
Programming will span more than 20 pediatric specialties, including cardiology, hematology, oncology, neurology, neurosurgery and orthopedics, alongside primary care, outpatient surgery, diagnostic imaging, occupational and physical therapy, audiology and pharmacy services. Several components are firsts for the system, including the first BJC HealthCare and WashU Medicine pediatric urgent care in the Wentzville area, a four bed overnight sleep lab that is the first at any of the specialty care centers, and a Young Athlete Center developed with WashU Medicine Orthopedics.
U.S. News & World Report ranked St. Louis Children’s Hospital first in Missouri and third in the Midwest in 2025, according to an announcement from the hospital. WashU Medicine physicians exclusively staff the facility’s parent hospital. The new center will rise at 45 Wentzville Parkway near the Highway 61 interchange.